Profile
- Name: Han, Sung Nim
- Current Position: Professor
- Major: Clinical Nutrition and Nutritional Immunology
- Research Areas: Relationship between obesity and immune function, Effects of vitamin D on immune cell differentiation and function, Effects of dietary fat on immune and inflammatory responses, Effects of obesity on mineral and vitamin metabolisms, Precision nutrition
- Office: +82-2-880-6836
- E-mail: shhan@snu.ac.kr
Education
- 1983.3-1987.2 Food and Nutrition, Seoul National University, BS
- 1988.3-1990.2 Food and Nutrition, Seoul National University, MS
- 1993.9-1999.5 Tufts University (Ph.D.)
Employment/Experience
- 2016. 3-present Professor, Department of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.
- 2014.7-2016.7 Deputy Vice President of Student Affairs, Seoul National University
- 2013.9-2014.8 Visiting Scientist, Nutritional Immunology Lab, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
- 2011.9-2016.8 Associate Professor, Department of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.
- 2007.9-2011.8 Assistant Professor, Department of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.
- 2004.6-2007.8 Scientist II, Nutritional Immunology Lab, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
- 2003.11-2007.8 Assistant Professor, The Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University, Boston, MA, USA
- 2002.2-2004.6 Scientist III, Nutritional Immunology Lab, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
- 2000.9– 2002.1 Research Associate, Nutritional Immunology Lab, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
- 1999.10–2000.8 Dietetic Intern, Brigham and Women’s Hospital, Boston, MA, USA
Recent Publications (Since 2018)
- Journal of Lipid and Atherosclerosis 12(3): 323-328, 2023 (doi:10.12997/jla.2023.12.3.323)
- GY Lee, K-M Chung, J Lee, J_H Kim, SN Han. Changes in anxiety and depression levels and meat intake following recognition of low genetic risk for high body mass index, triglycerides, and lipoproteins: A randomized controlled trial. PLoS ONE, 18(9): e0291052, 2023 (doi:10.1371/journal.pone.0291052)
- Upcycled Food: Definition, Consumer Awareness, and Utilization of By-products from Food Supply Chain. Journal of Korean Society of Food Culture, 38(4):191-202, 2023 (doi:10.7318/KJFC/2023.38.4.191)
- J So, K-M Chung, J Seo, B Kim, H Chun, SN Han, I-M Chung. High intake of sweet foods and low life satisfaction can act as risk factors for acute coronary syndrome through synergistic interaction. Frontiers in Nutrition, 10:1221916, 2023 (doi:10.3389/frnut.2023.1221916)
- TY Kim, CY Park, SN Han. Effect of cinacalcet-mediated parathyroid hormone reduction on vitamin D metabolism in high-fat diet-induced obese mice. Journal of Nutrition and Health, 56(1): 1-11, 2023 (doi: 10.4163/jnh.2023.56.1)
- U Shin, H You, GY Lee, Y Son, SN Han. The effects of 1,25(OH)2D3 treatment on metabolic reprogramming and maturation in bone marrow-derived dendritic cells from control and diabetic mice. Journal of Steroid Biochemistry and Molecular Biology, 225: 106197, 2023 (doi: 10.1016/j.jsbmb.2022.106197)
- DH Cho, GY Lee, JH An, SN Han. The effects of 1,25(OH)2D3 treatment on maturation and intracellular metabolic pathways of bone marrow-derived dendritic cells from lean and obese mice. IUBMB Life, 74(5): 378-390, 2022 (doi: 10.1002/iub.2592)
- SJ Kim, DH Cho, GY Lee, JH An, SN Han. The effects of dietary vitamin D supplementation and in vitro 1,25 dihydroxyvitamin D3 treatment on autophagy in bone marrow-derived dendritic cells from high fat diet-induced obese mice. Journal of Nutritional Biochemistry, 100: 108880, 2022 (doi: 10.1016/j.jnutbio.2021.108880)
- S Shin, S Park, Y Lim, SN Han. Dietary supplementation with Korean pine nut oil decreases body fat accumulation and dysregulation of the appetite-suppressing pathway in the hypothalamus of high-fat diet-induced obese mice. Nutrition Research and Practice, 16(3): 285-297, 2022 (doi: 10.4162/nrp.2022.16.3.285)
- GY Lee and SN Han. Direct-to-consumer genetic testing in Korea: current status and significance in clinical nutrition. Clinical Nutrition Research 10(4): 279-291, 2021. (doi: 10.7762/cnr.2021.10.4.279)
- CY Park, SK Lee, J Kim, D Kim, H Choe, J-H Jeong, K-C Choi, HS Park, SN Han, YJ Jang. Endoplasmic reticulum stress increases LECT2 expression via ATF4. Biochemical and Biophysical Research Communications 585:169-176, 2021 (doi: 10.1016/j.bbrc.2021.11.038)
- S Shin, Y Lim, J Chung, S Park, SN Han. Effects of Korean pine nut oil on the hepatic iron, copper, and zinc status and expression of genes and proteins related with iron absorption in diet-induced obese mice. Journal of Nutrition and Health 54(5):435-447, 2021 (doi: 10.4163/jnh.2021.54.5.435)
- H-K Kim, CY Park, SN Han. Nutrient modulation of viral infection-implications for COVID-19. Nutrition Research and Practice 15(Supplement): S1-S21, 2021 (doi:10.4162/nrp.2021.15.S1.S1)
- J-N Kam, SN Han, H-K Kim. Anti-inflammatory and anti-diabetic effect of black Soybean Anthocyanins: Data from a dual cooperative cellular system. Molecules 26: 3363, 2021. (doi: 10.3390/molecules26113363)
- MS Kang, CY Park, GY Lee, DH Cho, SJ Kim, SN Han. Effects of in vitro Vitamin D Treatment on Function of T cells and Autophagy Mechanisms in High-Fat Diet-Induced Obese Mice. Nutrition Research and Practice 15(6):673-685, 2021 (doi: 10.4162/nrp.2021.15.6.673)
- CY Park and SN Han. The role of vitamin D in adipose tissue biology: adipocyte differentiation, energy metabolism and inflammation. Journal of Lipid and Atherosclerosis, 10(2): 130-144, 2021 (doi: 10.12997/jla.2021.10.2.130)
- JH An, DH Cho, GY Lee, MS Kang, SJ Kim, SN Han. Effects of vitamin D supplementation on CD4+ T cell subsets and mTOR signaling pathway in high-fat-diet-induced obese mice. Nutrients 13; 796, 2021. (doi: 10.3390/nu13030796)
- KS Cha, CY Park, SE Lee, TY Kim, SN Han. The effects of 1,25-dihydroxyvitamin D3 on markers related to the differentiation and maturation of bone marrow-derived dendritic cells from control and obese mice. Journal of Nutritional Biochemistry, 2020 (doi: 10.1016/j.jnutbio.2020.108464)
- YK Seo, H Lee, H Kim, TY Kim, H Ryu, DL Ju, M Jang, KH Oh, C Ahn, SN Han. Foods contributing to nutrients intake and assessment of nutritional status in pre-dialysis patients : a cross-sectional study. BMC Nephrology, 21: 301, 2020 (doi: 10.1186/s12882-020-01958-8)
- CY Park, Y Shin, J-H Kim, S Zhu, YS Jung, SN Han. Effects of high fat diet-induced obesity on vitamin D metabolism and tissue distribution in vitamin D deficient or supplemented mice. Nutrition & Metabolism 17: 44, 2020. (doi: 10.1186/s12986-020-00463-x)
- H Lee, H Kim, TY Kim, H Ryu, DL Ju, M Jang, K-H Oh, C Ahn, SN Han. Dietary Assessment of Korean Non-dialysis Chronic Kidney Disease Patients based on the Diabetes Mellitus Comorbidity and Kidney Function. Journal of Korean Medical Science 35(23):e181, 2020. (doi: 10.3346/jkms.2020.35.e181)
- CY Park, TY Kim, JS Yoo, YK Seo, M Pae, SN Han. Effects of 1,25-dihydroxyvitamin D3 on the inflammatory responses of stromal vascular cells and adipocytes from lean and obese mice. Nutrients 12(2); 364, 2020 (doi:10.3390/nu12020364)
- CH Jin, Y So, H-Y Kim, SN Han, J-BKim. Anti-arthritic activities of supercritical carbon dioxide extract derived from radiation mutant Perilla frutescens var. Crispa in collagen antibody-induced arthritis. Nutrients 11;2959 doi:10.3390/nu1122959, 2019
- Yoo JS, CY Park, YK Seo, SH Woo, DY Kim, SN Han. Vitamin D supplementation partially affects colonic changes in dextran sulfate sodium-induced colitis obese mice but not lean mice. Nutrition Research 67:90-99, 2019 (doi: 10.1016/j.nutres.2019.03.009)
- H-K Kim, SN Han. Vitamin E: Regulatory role on gene and protein expression and metabolomics profiles. IUBMB Life 71(4):442-455, 2019 (doi: 10.1002/iub.2003)
- GY Lee, SN Han. The role of vitamin E in immunity. Nutrients 2018; 10: 1614.(doi: 10.3390/nu10111614)
- YS Jung, D Wu, D Smith, SN Meydani, SN Han. Dysregulated 1,25-dihydroxyvitamin D levels in high fat diet-induced obesity can be restored by changing to a lower fat diet in mice. Nutrition Research 53:51-60, 2018. (doi: 10.1016/j.nutres.2018.03.008)
- GY Lee, CY Park, KS Cha, SE Lee, M Pae, SN Han. Differential effects of dietary vitamin D supplementation on natural killer cell activity in lean and obese mice. Journal of Nutritional Biochemistry 55: 178-184, 2018 (doi: 10.1016/j.nutres.2018.03.008)
- HK Oh, JY Lee, WK Eo, SW Yoon, SN Han. Elevated Serum Vitamin B12 levels as a prognostic factor for survival time in metastatic cancer patients:A retrospective study. Nutrition and Cancer 70(1):37-44, 2018.
Grants
- Modulation of autophagy by obesity and vitamin D and its effects on differentiation and function of immune cells Role: Principle Investigator Funding agency: National Research Foundation of Korea Period: 6/1/18-5/31/21
- Impact of DTC genetic information disclosure on psychological factors, dietary intake and health-related behavior Role: Principle Investigator Funding agency: Seoul National University Period: 8/1/18-2/29/20
- Needs assessment and feasibility study for the development of Nutritional Science department in Mongolian National University of Medical Sciences Role: Principle Investigator Funding agency: National Research Foundation of Korea and Korean Ministry of Education Period: 4/1/19-1/31/20
- Strengthening of the educational competency of MNUMS nutrition department and the development of short-term nutritional training program: Role: Principle Investigator Funding agency: National Research Foundation of Korea and Korean Ministry of Education Period: 6/1/20-4/30/21
- Modulation of Immune Function and Immunometabolism by Vitamin D in Metabolic Disease Models: Role: Principle Investigator Funding agency: National Research Foundation of Korea Period: 3/1/21-2/28/24
